ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Endocrinology 2019;160:2165–2179This paper characterize viral insulin/IGF-1–like peptides (VILPs), which the authors identified in four members of the Iridoviridae family - viruses with double-stranded DNA genomes, which are found in amphibians, fish, and invertebrates. VILPs can bind to human insulin and IGF-1 receptors and stimulate classic post-receptor signaling pathways. They can stimulate glucose uptake...